摘要
目的探讨经皮附睾穿刺取精术(PESA)获得精子经冷冻复苏后行卵胞浆内单精子注射术(ICSI)的临床效果。方法将采用新鲜附睾精子的94例患者作为新鲜组对照,冷冻复苏后附睾精子的92例患者作为冻精组,比较二组的受精率,可利用胚胎率及妊娠率。结果新鲜组与冻精组相比受精率,可利用胚胎率及妊娠率无显著性差异(75.04%vs78.4%,78.3%vs81.3%,47.87%vs44.44%P>0.05)。结论PESA精子经冷冻后有很好的复苏率(97.94%),结合ICSI可得到与使用新鲜PESA精子同样的临床结局,可作为梗阻性无精症的治疗方法。
Objective: To investigate the outcomes of frozen- thawed sperm obtained from percutaneous epididymal sperm aspiration (PESA). Methods: Fresh sperm from PESA was used in 94 couples for ICSI (fresh group), frozen -thawed sperm from PESA was used in 92 couples for ICSI ( frozen group). Fertilization rate, embryo quality and pregnancy rate were compared between the two groups. Results: There was no statistically significant difference in fertilization rate, embryo quality and pregnancy rate between the two groups (75. 04% vs 78.4%, 78. 3% vs 81.3%, 47. 87% vs 44. 44%, P 〉0. 05). Conclusion: The clinical outcomes are similar between fresh and frozen - thawed sperm from PESA. PESA combined with sperm cryopreservation may apply to treatment for some patients with azoospermia.
出处
《中国优生与遗传杂志》
2009年第12期96-98,共3页
Chinese Journal of Birth Health & Heredity