金乌骨通片中葛根素的含量分析

Content analysis of kakkonein in jin wu gu tong tablets

目的检测金乌骨通片中葛根系的含量,为建立金乌骨通片的质量标准作基础研究。方法采用高效液相色谱法对制剂中葛根素进行定量分析。结果葛根供试品溶液呈现与对照品溶液色谱保留时间相同的色谱峰;本品每片含葛根以葛根素计,不得少于1.3 mg。结论所建立之方法可靠、准确,可作为金乌骨通片的质量控制。

Objective To establish the quality control standard of jin wu gu tong tablets by detecting the contents of kakkonein in them.Methods High-performance liquid chromatography was employed to analyze the contents of kakkonein quantitatively.Results Kakkonein solutions for detection showed the same chromatograph peaks as the reference substances in chromatograph retention time.The amount recorded by kakkonein in every tablet was no more than 1.3 mg.Conclusion The method is reliable,accurate and it can be used as the quality control standard for jin wu gu tong tablets.