抗艾滋病中成药唐草片抗氧化性的研究

Study on Anti-oxidation Effect of Tangcao Tablets

目的:研究唐草片对羟自由基的清除作用。方法:采用分光光度法考察唐草片对Fenton反应产生的羟基自由基的清除作用,并采用维生素C作为阳性对照。利用大孔树脂对其中的抗氧化成分进行初步分离。结果:唐草片具有较好的羟自由基清除作用,且呈剂量依赖性,发现其中所含的总黄酮类成分作用较强。结论:唐草片具有一定的抗氧化性。

Objective： To investigate hydroxyl radical scavenging effects of Tangcao tablets. Methods： Spectrophotometry was employed to evaluate scavenging of hydroxyl radicals which were produced by the Fenton reaction. Vitamin C was used as positive control. Active ingredients were separated with macroporous resin. Results： The results indicated that Tangcao tablets had dose-dependent hydroxyl radical scavenging activity. And the flavonoids contained showed high activity. Conclusion： Tangcao tablets have high anti-oxidative activity.