200例住院患者抗菌药物使用情况分析

Analysis of the use of antibacterial drugs in cases of 200 inpatients

目的了解住院患者抗菌药物的使用情况,为抗菌药物的合理使用和科学管理提供依据。方法采用回顾性调查方法,随机抽取出院患者病历200份,统计抗菌药物用药频率、药物利用指数和联合用药品种,根据《抗菌药物临床应用指导原则》,分析抗菌药物使用情况。结果200份出院病历中99%的患者使用了抗菌药物,出现的问题为抗菌药用药频率过多、给药时间不合理、用药时间偏长和日给药次数不当。头孢曲松药物利用指数最高,头孢噻肟用药频率最多。结论住院患者抗菌药物应用存在不合理之处,需进一步改进,以提高合理用药水平。

Objective To understand the inpatients＇ use of antibacterial drugs and to provide a basis for the reasonable use and the scientific management of antimicrobial drugs. Methods With a retrospective survey method, 200 medical records of patients discharged from hospital were randomly selected and the statistics of the frequency of use of antimicrobial drugs, drug uti- lization index and the variety of combination therapy were made. Under the Guiding principles of clinical use of antibacterial drugs, reasonable use of antibacterial drug was evaluated. Results The administration of antibacterial drugs was 99% in the medical record of patients discharged from hospital. The antibacterial drug frequency was too high. The administration time of an- tibacterial drugs was too long and unreasonable, and the defined daily dose was unsuitable. The drug utilization index of ceftriaxone was on the highest but the drug administration frequency of cefotaxime was the highest. Conclusion There are some unreasonable cases in the use of antibacterial drugs in inpatients. In order to raise the rational drug use level, further improvements are necessary.