女性高血压人群血脂水平与缺血性卒中的相关性

Correlation between the level of blood lipids and the risk of ischemic strokein women with hypertension

目的 探讨女性高血压人群血脂水平与缺血性卒中的关系。方法对3607例女性原发性高血压病患者进行流行病学调查和实验室检查，通过Logistic回归获得各类血脂水平对缺血性卒中的风险率及95％可信区间（a）。结果调整各种混杂因素后，非高密度脂蛋白胆固醇（non-HDL-C）和总胆固醇与高密度脂蛋白胆固醇比率（TC／HDL—C）与缺血性卒中显著相关，OR分别为1．253（95％CI，1．039～1．512）和1．594（95％C1，1．267～2．006）。结论non-HDL和TC／HDL—C是女性高血压人群缺血性卒中独立的预测因子。

Objective To evaluate the correlation between the level of blood lipids and the risk of ischemic stroke in women with hypertension. Methods An epidemiological studies and laboratory assess to a resident group of 3 607 women with hypertension were conducted. Odds ratios （OR） and 95% confidence intervals （CI） for ischemie stroke were calculated by using logistic regression. Results After adjusting for independent variables, non-HDL cholesterol （non-HDL-C） and TC： HDL-C ratio had a significant association with ischemic stroke. The adjusted OR and CI were 1. 253 （95% CI, 1.039-1.512） and 1.594（95%CI, 1.267-2.006） respectively. Conclusions Non-HDL-C and TC： HDL-C ratio are the independent risk factor for ischemic stroke in women.