PLT、CRP变化及SIRS评分对老年感染中毒症患者预后的影响

Effects of the changes of platelet,CRP and SIRS score on the prognosis of the aged patients with sepsis

目的探讨血小板计数(PLT)、C反应蛋白(CRP)的变化及SIRS评分对老年感染中毒症患者预后的影响。方法将126例老年感染患者按照国际感染中毒症会议制定的诊断标准分为感染中毒症患者96例(观察组)和单纯感染患者30例(对照组),比较两组血清PLT、CRP的变化及SIRS评分。结果观察组PLT明显低于对照组,CRP明显高于对照组。观察组死亡者(36例)PLT明显低于生存者(60例),随SIRS评分分值增高,病死率有增加趋势。结论PLT、CRP及SIRS评分可用于评估老年感染中毒症预后并指导治疗。

Objective To investigate the changes of platelet （PLT）, C-reactive protein （CRP）, SIRS score on the prognosis of the aged patients with sepsis. Methods One hundred and twenty-six aged patients with infectious diseases were divided into sepsis group （n = 96） and control group （n = 30） according to the International Sepsis Definitions. PLT, CRP and SIRS score were analyzed between the two groups. Results PLT in sepsis group was lower than that in the control group, while the CRP was higher. And for the sepsis group, PLT of non-survival patients was lower than that of survival patients. The mortality increased with the increase of SIRS score. Conclusion PLT, CRP and SIRS score are helpful to evaluate the prognosis and direct treatment of the aged patients with sepsis.