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血清半胱氨酸蛋白酶抑制剂C与尿微量白蛋白联合检测对原发性高血压肾损害的诊断价值 被引量：2

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摘要 目的评价血清半胱氨酸蛋白酶抑制剂C(简称Cystatin C)和尿微量白蛋白(U-mAlb)在诊断高血压肾损害的临床应用。方法对68例高血压患者和35例健康体检者分别进行血肌酐、血清CystatinC和U-mAlb浓度测定,比较其结果。结果U-mAlb在肌酐清除率(Ccr)>80ml/min时与对照组相比已经开始升高(P<0.01),血清CystatinC升高晚于U-mAlb,在Ccr为50～80ml/min时与对照组相比差异有高度显著性(P<0.01)。结论在诊断原发性高血压肾损害时,U-mAlb比CystatinC有更好的敏感度,两项指标联合检测有助于提高诊断准确率。
作者 吴建红 朱蔚
机构地区 江苏省昆山市第一人民医院检验科 江苏省昆山市中医医院检验科
出处 《右江民族医学院学报》 2009年第6期980-981,共2页 Journal of Youjiang Medical University for Nationalities
关键词 高血压 尿微量白蛋白 半胱氨酸蛋白酶抑制剂C
分类号 R446.1 [医药卫生—诊断学]
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参考文献6

二级参考文献23

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共引文献257

同被引文献40

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右江民族医学院学报
2009年 第6期

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