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振动对骨重建影响的三维有限元分析 被引量：2

Three-Dimensional Finite Element Analysis of Vibration on Bone Rebuilding
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摘要 目的观察不同振动频率刺激下股骨表观密度的变化情况,从而确定何种振动参数能对骨骼系统产生最有益影响。方法先获得兔股骨扫描图像,再利用UG软件对图像进行三维重建得到股骨的实体模型,最后导入ANSYS软件中,利用ANSYS软件布尔操作中的减操作,得到带有空腔的兔股骨生物力学模型。结果通过有限元仿真分析,发现添加振动激励后骨骼的应力分布和骨密度发生了变化,股骨部分部位骨密度增加。结论有限元分析不但为分析振动对骨重建的动物和人体实验打下基础,还为进一步深入了解骨骼结构与力学环境之间的关系、为进一步研究对抗航天失重引起的骨丢失和治疗骨质疏松症提供了帮助。 Objective Observing the changes of rabbit femur surface density induced by different vibration frequency stimulation, to ascertain what vibration parameter can bring beneficial influence on the bone system. Methods Firstly the scanning images of rabbit femur were obtained. Then making use of the software of UG to carry on the three-dimension reconstruction, solid model of femur was got. At last, putting the model into the ANSYS software, the rabbit femur biomechanics model with marrow cavity was completed by subtract operation. Results By finite element analysis, we found vibration stimulation changed the femur stress distribution and improved bone mineral density in some parts of femur. Conclusion Finite element analysis not only founds the basis of animal and human experiment for the influence of vibration on femur bone rebuilding and understands the relation between bone structure and mechanics environment uheriorly, but also provides a help for preventing bone loss in weightlessness and treating osteoporosis.
作者 李志香 马超 张春林
机构地区 北京理工大学机械与车辆工程学院
出处 《北京生物医学工程》 2009年第6期565-568,共4页 Beijing Biomedical Engineering
基金 国防科工委基础研究项目(K1302060610)资助
关键词 骨重建 振动 三维模型 有限元分析 bone rebuilding vibration three-dimensional modal finite element analysis
分类号 R318.01 [医药卫生—生物医学工程]
  • 相关文献

参考文献12

  • 1Clinton Rubin, McLeod KJ. Promotion of bony ingrowth by frequency-specific, low-amplitude mechanical strain[ J]. Clinical Orthopaedics and Related Research, 1994, 298(8) : 165 - 174.
  • 2Clinton Rubin, Steven Bain. Low mechanical signs strengthen long bone[J]. Nature, 2001, 412(8): 603 -604.
  • 3Clinton Rubin. The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low- magnitude mechanical stimuli[ J] . The FASEB Journal, 2001, 15(12) : 2225 -2229.
  • 4Rubin C, Judex S, Q in YX ,et al. Inhibition of osteopenia by low magnitude, high frequency mechanical stimuli [ J ]. Drug Discovery Today, 2001, 6(16) :848 -858.
  • 5Judex Stefan, Boyd Steve, Rubin Clintion, et al. Adaptations of trabecular bone to low magnitude vibrations result in more uniform stress and strain under load [ J ]. Annals of Biomedical Engineering, 2003, 31(1 ):12-20.
  • 6Clinton Rubin, Robert Recker, Diane Cullen, et al. Prevention of postmenopausal bone loss by a low-magnitude, high-frequency mechanical stimuli: a clinical trial assessing compliance, efficacy, and safety [ J ]. Bone & Mineral Research, 2004, 19 (3) :343-351.
  • 7Russo, Fulvio Lauretani, Stefania Bandinelli, et al. High- frequency vibration training increases muscle power in postmenopausal women[ J]. Arch Phys Med Rehabil, 2003 , 84 (12) :1854-1857.
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二级参考文献13

  • 1朱兴华,白凤德,董心,王晓迎.三面固定槽形加压钢板内固定后股骨表面再造模拟[J].中国生物医学工程学报,1997,16(2):128-132. 被引量：14
  • 2Barry,Patrick L.Good vibrations:a new treatment study by NASA-funded doctors could reverse bone loss experienced by astronauts in space[EB].[2002-05-04].http://science.nasa.gov/headlines/y2001/sdt02nov 1.htm.
  • 3NSBRI Bone Loss Team Strategic Plan[EB].[2003]http://www.nsbri.org/Research/StrategicPlans/BoneLoss.
  • 4Goodship AE,Cunningham JL,Oganov V,et al.Bone loss during long term space flight is prevented by the application of a short term impulsive mechanical stimulus[J].Acta Astronautica,1998,43(3-6):65-75.
  • 5Rubin C,McLeod KJ.Promotion of bony ingrowth by frequency-specific,low-amplitude mechanical strain[J].Clinical Orthopaedics and Related Research,1994,298(8):165-174.
  • 6Rubin C,Bain S.Low mechanical signs strengthen long bone[J].Nature,2001,412(8):603-604.
  • 7Rubin C.The anabolic activity of bone tissue,suppressed by disuse,is normalized by brief exposure to extremely low-magnitude mechanical stimuli[J].The FASEB Journal,2001,15(12):2225-2229.
  • 8Rubin S,Judex YXQ.Inhibition of osteopenia by low magnitude,high frequency mechanical stimuli[J].Drug Discovery Today,2001,6(16):848-858.
  • 9Judex S,Boyd S,Rubin C,et al.Adaptations of trabecular bone to low magnitude vibrations result in more uniform stress and strain under load[J].Annals of Biomedical Engineering,2003,31(1):12-20.
  • 10Rubin C,Recker R,Cullen D,et al.Prevention of postmenopausal bone loss by a low-magnitude,high-frequency mechanical stimuli:a clinical trial assessing compliance,efficacy,and safety[J].Bone & Mineral Research,2004,19(3):343-351.

共引文献20

同被引文献13

引证文献2

二级引证文献8

北京生物医学工程
2009年 第6期

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