脑电图空间对称指数在评价颈动脉支架置入术后脑血流灌注中的应用

Evaluation of cerebral blood flow with spatial brain symmetry index in patients performed carotid artery stenting

目的探讨脑电图空间对称指数（sBSI）在颈动脉支架置入术（CAS）前后的变化。方法对31例CAS患者在术前1d和术后3～5d内分别行脑电图检查，计算出脑电图sBSI。根据脑血管造影的结果评估患者的术前狭窄程度和术后残余狭窄。采用配对t检验对CAS前后sBSI进行比较分析，同时对脑电图sBSI手术前后改善程度与狭窄改善程度和术前sBSI进行直线相关和回归分析。结果31例患者CAS术后脑电图sBSI较术前出现明显的降低，差异有统计学意义（P〈0．05）。将脑电图sBSI手术前后改善程度与狭窄改善程度进行相关分析后发现，两者无显著相关性（P〉0．05），脑电图sBSI手术前后改善程度与术前脑电图sBSI具有显著正相关（P〈0．05）。结论CAS术后脑电图sBSI存在变化，脑电图sBSI检查可作为评价CAS术后脑血流灌注增加的一种安全、有效的方法。

Objective To detect the spatial brain symmetry index （sBSI） changes, reflected the blood flow changes, before and after the carotid artery stenting （CAS）. Methods Thirty one patients performed CAS were examined with electroencephalogram 1 d before and 3-5 d after the procedures. We analyzed the sBSI of EEG. The preoperative and postoperative degrees of stenosis were determined according to cerebral angiography. The sBSI changes were compared using paired analysis before and after the procedures. Correlation and regression analysis was processed between EEG sBSI improvement and both stenosis decrement and preoperative sBSI. Results The sBSI of 31 patients were significantly different before and after the stenting （P〈0.05）. No correlation between the sBSI improvement and the degree of stenosis reduction was found （P〉0.05）. The sBSI improvement was positively correlated with sBSI before stenting. Conclusions Electroencephalogram spatial brain symmetry index can be regarded as a safe and effective index to evaluate the improved effect of CAS in patients with carotid artery stenosis.