阿替卡因与利多卡因在儿童牙体牙髓治疗中麻醉效果的研究比较

Comparative Study for Articaine and Lidocaine in Children's Tooth and Endodontic Therapy

目的比较阿替卡因与利多卡因（均含有肾上腺素）在儿童牙体牙髓治疗中的有效率。方泫本组88例5～10岁儿童乳磨牙、第一恒磨牙牙髓炎的患者，采用随机双盲法进行阿替卡因或者利多卡因的浸润麻醉。注射后5min评价麻醉效果。结果阿替卡因在上、下颌乳磨牙麻醉的有效率都为100％，第一恒磨牙麻醉有效率为92．86％；利多卡因在上颌乳磨牙有效率是75．0％，下颌乳磨牙是55．56％，第一恒磨牙是35．70％。阿替卡因与利多卡因麻醉效果在下颌乳磨牙和第一恒磨牙的差异，有统计学意义（P〈0．05）。结论阿替卡因在下颌乳磨牙和第一恒磨牙浸润麻醉效果强于利多卡因。

Objective To compare the anesthetic efficacy of articaine and lidocaine （both with epinephrine） in children＇ s tooth and endodontic therapy. Methods 88 patients were administered by means of infiltration anesthesia. The effect of anesthesia was evaluated by patients and doctors. Results The success rate for maxillary and mandibular deciduous molar using articaine were 100%. 92.86% in the first molar,whereas for the lidocaine, success rate was 75.0% in the maxillary deciduous molar, 55.56% in the mandibular deciduous molar and 35.70% in the first molar. There was sta- tistical significant difference between the articaine and lidocaine solution （ P 〈 0.05）. Conclusion The efficacy of articaine is superior to lidoeaine for mandibular deciduous molar and first molar.