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α-硫辛酸治疗糖尿病周围神经病变的疗效观察 被引量：7

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摘要 目的评价α-硫辛酸治疗糖尿病周围神经病变的疗效,及是否能改善神经传导速度。方法对60例2型糖尿病伴有不同程度神经病变患者随机分成两组,对照组静脉注射甲钴胺(弥可保:生产批号2006-01-19)500μg加入0.9%生理盐水10mL,每日1次,治疗组在对照组基础上每日静脉滴注α-硫辛酸(唐可停:生产批号06011921,上海现代哈森药业有限公司)600mg加入0.9%生理盐水250mL中,连续2周观察疗效。结果症状改善率两组比较治疗组优于对照组(P<0.05),神经传导速度(NCV)改善率两组比较,P<0.05。结论α-硫辛酸可以明显提高DPN患者NCV,改善症状,疗效优于单独使用甲钴胺,临床值得推广,无不良反应发生。
作者 辛月颖
机构地区 沈阳市第四人民医院内分泌科
出处 《中国现代医生》 2009年第34期45-45,50,共2页 China Modern Doctor
关键词 Α-硫辛酸 甲钴胺 糖尿病周围神经病变
分类号 R587.1 [医药卫生—内分泌]
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中国现代医生
2009年 第34期

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