辛伐他汀联合氯吡格雷、低分子肝素钙治疗不稳定型心绞痛疗效观察

Clinical Observation On Treatment Of Simvastatin、Clopidogrel Combined With Low Molecular Heparin Calcium On Unstable Anginapectoris

目的观察辛伐他汀联合氯吡格雷、低分子肝素钙治疗不稳定型心绞痛(UAP)的治疗疗效。方法UAP 84例,随机分为对照组42例、治疗组42例。两组均进行严格内科药物治疗,治疗组在上述治疗的基础上给予辛伐他汀、氯吡格雷、皮下注射低分子肝素钙5000u,比较两组心绞痛发作,心电图变化及血脂变化。结果对照组的总有效率76.2%,治疗组为90.5%,两组比较差异有统计学意义(P<0.05)。结论辛伐他汀联合氯吡格雷、低分子肝素钙、治疗不稳定型心绞痛,可降低心肌梗死发生率,疗效显著,副作用小。

Objective The primary aim of the study was to investigate the effect of sinvastatin,clopidogrel and low molecular heparin in treatment of unstable angina pectoris（UAP）.Methods Eighty-four patients with UAP were randomized into experiment group（42）,simvastatin、clopidogrel and low molecular weight heparin 5000u;and the control group（42）,The ECG episode times and detected and ch.Results The experiment group had better cardiovascular outcomes than the control group（90.5%vs 76.2%,P〈0.05）.Conclusion Short-term treatment with Simvastatin,clopidogrel and low molecular weight heparin can reduce the incidence of myocardial infarction in unstable angina pectoris.In addition,the side effects of our treatment could be neglected.