纳米羟基磷灰石-聚(己内酯-丙交酯)共聚物复合材料

Composite of Hydroxyapatite Nanoparticles Poly(ε-caprolactone-co-lactide)

通过纳米羟基磷灰石(HA)的羟基引发ε-己内酯(ε-CL)开环聚合,再接枝不同量的丙交酯(LA),制备了HA-P(CL-LA)复合材料。采用TEM、FT-IR、1H-NMR、13C-NMR等对复合物的结构进行了表征。结果表明:HA在复合物中的分散较均匀,并且保持了原来的针状或棒状形貌;共聚物中n(ε-CL)/n(LA)随着单体投料中n(ε-CL)/n(LA)的增加而增加;样品在制备过程中没有发生丙交酯与己内酯之间的酯交换,只发生了丙交酯自身的酯交换,共聚物中丙交酯链段主要以全同序列为主。

Hydroxyapatite nanoparticles were surface-grafted with ε-caprolactone （ε-CL） by the ring- opening polymerization, and different quantity of lactides were segmented on the particles. The structure of the composite is characterized by TEM, FT-IR, ^1H-NMR and ^13C-NMR. The results indicate that HA has been dispersed homogeneously in the composites and kept original acicular or rod morphology. With the feeding ratio of ε-caprolactone to lactide （molar ratio） increasing, the molar ratio of caprolactone units to lactide units in the copolymer increases. No transesterification between caprolactone and lactide is observed. The transesterification of lactide occurs, but the segment of PLA in the copolyrner gives priovity to isotactic sequence mainly.