脑梗死患者记忆障碍与情感障碍的研究

Memory impairment in patients with cerebral infarction and the study of affective disorder

目的本文通过对脑梗死所致记忆障碍与情感障碍进行研究,明确记忆障碍及情感障碍与脑损害部位是否有必然联系,探索记忆障碍和情感障碍的相互影响。方法收集神经内科住院的初次脑梗死患者80例,正常对照组40例。分别进行记忆功能测定、情感测定以及MRI各项指标的测量,然后进行统计分析。结果正常组和脑梗死组记忆功能障碍有显著性差异(P<0.001)。脑梗死体积、数量和部位不同,其记忆障碍和情感障碍均有显著性差异(P<0.05)。左侧半球病变引起的记忆损害及情感障碍较右侧半球病变严重。结论脑梗死后记忆障碍和情感障碍发生率很高,且与梗死部位、容积、数量等显著相关,严重降低脑卒中患者的治疗效果和生活质量。

Objective Based on the memory impairment caused by cerebral infarction,to study affective disorder,a clear memory disorder and affective disorder and brain damage have a causal link,and explore barriers to memory impairment and emotional interaction.Methods The collection of the initial hospitalization in patients of Department of Neurology with cerebral infarction was 80 cases and 40 cases of normal control group.Memory and emotional function were measured,as well as MRI measurement were recorded for the purpose of statistical analysis.Results Normal group and memory dysfunction in cerebral infarction group were significantly different（P〈0.001）.Infarct volume,quantity and location is different from its memory impairment and affective disorder were significantly different（P〈0.05）.Lesions of left hemisphere caused more serious memory impairment and emotional obstacles than those of the right hemisphere.Conclusions Memory impairment after cerebral infarction and the high incidence of affective disorder showes correlation with the infarct location,volume and the number significantly,and are related to a serious decline in the effect of treatment and quality of life of stroke patients.