血清同型半胱氨酸的水平与心脑血管疾病的关系

The relationship between serum homocysteine level and cardio/cerebrovascular disease

目的探讨血清同型半胱氨酸水平与心脑血管疾病的关系。方法用循环酶法测定心脑血管疾病患者血清同型半胱氨酸水平,同时以100例健康体检者为对照。结果心脑血管疾病患者血清同型半胱氨酸水平明显高于健康人。结论血清高同型半胱氨酸是心脑血管病的一个危险因素,其水平随着冠心病程度加重而增加,脑血管病类型与血清同型半胱氨酸水平无关。

Objective To investigate the relationship between serum homocysteine （HCY） level and cardio/cerebrovascular disease. Methods Serum level of HCY in patients with cardio/cerebrovas- cular disease was determined by applying enzymatic cycling assay, and the test results were compared with those of 100 normal controls （healthy control group）. Results The serum HCY level of cardio/ cerebrovascular disease group was significantly higher than that of healthy control group. Conclusion Hyperhomocysteine （HHCY） is a risk factor for cardio/cerebrovascular disease, and its level is in creasing with severity of coronary heart disease （CHD）. The types of cerebrovascular disease were not associated with serum level of HCY.