摘要
目的:通过检测精索静脉曲张(VC)不育患者精索静脉结扎手术前后外周血生殖激素水平及精液参数,探讨患者手术前后生殖激素水平的变化与精液质量改善之间的关系及对手术效果的评价。方法:96例精索静脉曲张不育患者按精子密度分为A(精子密度≥20×106/ml)、B(5×106/ml<精子密度<20×106/ml)、C(精子密度≤5×106/ml)三个亚组,并对其进行手术前后精液分析及检测外周血生殖激素卵泡刺激素(FSH)、黄体生成素(LH)和睾酮(T)水平。结果:VC不育患者中,A、B、C各组FSH、LH手术前后生殖激素水平比较,差异有统计学意义(P<0.05),T在C组较术前降低。术后精液质量改善与术前相比,差异有统计学意义(P<0.05)。结论:VC可引起男性不育患者外周血FSH、LH、T水平的不同程度的变化,FSH和LH与精子密度的减少有关,且影响精子的质量。
Objective：To detect the levels of the reproductive hormone and the semen parameters of the peripheral venous blood from infertility patients with varicocele （VC） before and after operation,and to explore the relationships of the reproductive hormone levels changes and semen quality improvement in patients and evaluation of surgical results. Methods：According to the density of sperm,96 cases of infertility patients with VC were divided into three subgroups：A group （the density of sperm≥20×106/ml）,B group （5×106/mlthe density of sperm20×106/ml）,C group （the density of sperm≤5×106/ml）. To determine the semen quality and the levels of follicle stimulating hormone （FSH）,luteinizing hormone （LH） and testosterone （T） in the peripheral venous blood. Results：The levels of the serum FSH and LH in A,B,C subgroup was significantly higher than that in post-operative （P0.05）,only the levels of the serum T in C group was lower than that in post-operative. The sermon quality improvement after operation increased significantly compared with the pre-operative （P0.05）. Conclusion：VC can cause the change of different degrees on the levels of FSH,LH and T from infertility patients,there is a correlation between the levels of FSH,LH in the peripheral venous blood and the density of sperm.
出处
《中国医药导报》
CAS
2009年第36期59-60,共2页
China Medical Herald
