中医外治法治疗乳腺增生的临床研究

Clinical observation of therapeutic effect of external application of Chinese herbal medicine film plus acupoint-injection on breast hyperplasia

目的:观察中药膜外敷加穴位注射疗法治疗乳腺增生病的疗效。方法:将120例符合肝失疏泄型的乳腺增生病患者随机分为3组:治疗组(中药膜外敷加穴位注射)、穴位注射组和对照组各40例。观察3组综合疗效、症状与体征改善情况、血清性激素水平及彩超检查。结果:1个疗程后,治疗组疗效显著(P<0.05),穴位注射组疗效不明显(P>0.05)。2个疗程后,治疗组与穴位注射组与对照组比较均有显著疗效(P<0.05或P<0.01),但治疗组仍优于穴位注射组(P<0.05);治疗组和穴位注射组均能有效降低血清中泌乳素、雌二醇水平(P<0.01),但治疗组下降幅度明显优于穴位注射组(P<0.05);治疗组血清中孕酮水平出现升高(P<0.05)。结论:中药膜外敷加穴位注射疗法对肝失疏泄型乳腺增生病疗效可靠。

Objective：To observe the therapeutic effect ofexternal application ofChinese herbal medicine film plus acupoint-injection on breast hyperplasia.Methods：The 120 cases ofbreast hyperplasia with syndrome ofthe liver failing to maintain the normal flow ofqi were randomly divided into treatment group（40cases） which was treated by external application ofChinese herbal medicine film plus acupoint-injection, acupoint-injection group（40 cases） and control group（40cases）.The changes ofsymptoms and signs, level ofserum sexual hormone and color doppler ultrasound analysis ofthree group were observed for comparison.Results：After 1 course oftreatment, the total effective rate oftreatment group was obviously higher than that ofcontrol group（P〈0.05）.There was on obvious difference ofthe total effective rate between acupoint-injection group and control group（P〉0.05）.After 2 courses oftreatment, the total effective rate oftreatment group and acupoint-injection group was obviously higher than that ofcontrol group（P〈0.01 or P〈0.05）, and treatment group was significantly better than acupoint-injection group（P〈0.05）.The prolactin（PRL） and Estradiol（E2） oftwo groups decreased（P〈0.01）, and treatment group was better than acupoint-injection group（P〈0.05）.The progesterone（P） oftreatment group increased（P〈0.05）.Conclusion：External application ofChinese herbal medicine film plus acupoint-injection had reliable effect on breast hyperplasia with syndrome ofthe liver failing to maintain the normal flow ofqi.