W-F168-B型透析器复用机临床应用研究

Clinical Research of Dialyzer Reprocessing Machine W-F168-B

观察成都威力生生物材料公司生产的W-F168-B型透析器复用机临床应用的效果,了解其对透析器总血室容积(total cell volume,TCV)、受试者透析充分性的影响,并评估其消毒效果。符合纳入标准的受试者随机分为2组,试验组和对照组的透析器分别用W-F168-B和RENATRONⅡ(美国明泰科公司生产)复用。试验测定复用前后透析器的TCV,计算受试者的尿素清除率除以分布容积(Kt/V,K为尿素清除率,t为透析时间,V为分布容积),并采集受试者透析后血样行微生物培养。结果用均数±标准差表示,采用成组设计的t检验,spss13.0统计软件包分析。试验组、对照组复用前后TCV差值分别为5.5±4.15、4.5±2.56、P>0.05;Kt/V分别为1.25±0.26、1.24±0.19、P>0.05,t检验示结果均无统计学差异。血培养均未见细菌及真菌生长。试验结果表明,2种透析器复用机对透析器性能的影响及复用后的透析器对受试者透析充分性的影响均无明显差异,能达到较好的透析质量。

This is a research project aimed at investigating the clinical efficiency of W-F168-B, a dialyzer reprocessing machine made by Weilisheng Biological Material Company in Chengdu, evaluating its effects on total cell volume（TCV） and dialysis sufficiency, and assessing its disinfection efficacy. All subjects were randomly divided into two groups, whose dialyzers were reprocessed by W-F168-B （made in Chengdu） and RENATRON Ⅱ （made by MINNTECH Company in the United States） respectively. We detected TCV of the dialyzer before and after reusing and calculated their diversity. We also calculated all subjects＇Kt/V. The values of TCV diversities of two groups were 5.5±4.15 （experimental group） and 4.5±2.56 （control group） respectively, P〉0.05. The levels of Kt/V of ex- perimental group and control group were 1.25±0.26 and 1, 24±0.19, P〉0.05. T-test showed that there was no statistically significanct difference between the two groups. The result of every hemoculture is negative. In conclusion, these two dialyzer reprocessing machines are similar in the effect of the dialyzer＇s performance and the subject＇s dialysis sufficiency. The reused dialyzers reprocessed by these two machines are safe for use.