42例鼻后滴漏综合征致儿童慢性咳嗽临床分析

Clinical analysis on 42 children cases with chronic cough complicated from postnasal drip syndrome(PNDs )

目的探讨以慢性咳嗽为主要表现的儿童鼻后滴漏综合征诊断和治疗程序。方法以慢性咳嗽为主要表现并确诊为鼻后滴漏综合征的儿童患者42例,采用抗炎与抗变态反应疗法以及必要的手术疗法进行治疗;疗程结束后,以主观症状改善程度作为评价指标,综合分析患儿临床特点及其治疗反应性,并随访3个月以上。结果本组患儿中,治愈30例(71.42%),好转12例(28.58%),总有效率100%。结论表现为鼻后滴漏综合征的儿童鼻-鼻窦疾病可以并发慢性咳嗽,并可能以此为主要临床特点。积极治疗鼻-鼻窦疾病,可以有效地消除该类继发性咳嗽症状。

Objective To explore the feasible procedures for the diagnosis and treatment of children with chronic cough as the main manifestation of postnasal drip syndrome （PNDs） based on a clinical trial. Methods Included in this study were 42 children cases with PNDs manifested themselves as chronic cough as the main clinical presentations. They were actively treated by anti-inflammatory and/or anti-allergic treatment, supplemented with necessary surgical procedures. Thereafter, all these children were followed up for more than 3 months and clinically evaluated with their improving levels of subjective symptoms as the main indicators to sum up the clinical characteristics of the lesion and therapeutic effect of the therapy on these cases by the end of following up period, following a careful analysis on their all clinical data. Results In this group of patients, 30 cases （71.42%） were clarified into the sub-group of cured, and 12 （28.58%） were clarified into the sub-group of improved, with a total effective rate so high as to 100%. Conclusions These children cases with PNDs, caused by the diseases in nasal cavity and/or sinuses, may manifest the symptom of chronic cough as their main clinical feature. Active treatment on these lesions can effectively cure this kind of secondary condition.