倍频532nm激光治疗视网膜血管性疾病所致黄斑水肿

532nm frequency-doubled laser photocoagulation for macular edema caused by retinal angiopathy

目的:探讨倍频532nm激光治疗视网膜血管性疾病所致黄斑水肿的临床效果。方法:对89例112眼视网膜血管性疾病所致黄斑水肿患者(糖尿病性视网膜病变53例75眼,视网膜静脉阻塞34例35眼,Coats病1例1眼,旁中心凹视网膜毛细血管扩张症1例1眼),采用倍频532nm激光行黄斑区局部或格栅样光凝治疗黄斑部的局部或弥漫性水肿。术后随访1a观察患者黄斑水肿消退情况和视力变化。结果:光凝治疗后视力提高者21眼(18.7%),不变者84眼(75.0%),下降者7眼(6.3%)。光凝后黄斑水肿完全吸收40眼(35.7%),部分吸收60眼(53.6%),无吸收12眼(10.7%)。且局限性黄斑水肿的治疗效果优于弥漫水肿及囊样水肿(P<0.01)。结论:倍频532nm激光光凝术是治疗视网膜血管性疾病所致黄斑水肿的有效、安全方法。

AIM： To investigate the effect of 532nm frequency- doubled laser photocoagulation treatment for macular edema caused by retinal angiopathy. METHODS： Eighhty-nine patients （112 eyes） with macular edema caused by retinal angiopathy were enrolled in this study. The topical or grid photocoagulation of macula was performed with 532nm frequency-doubled laser photocoagulation. Of them, localized edema was treated with direct photocoagulation and diffuse edema was treated with grid photocoagulation. The subsidence of the macular edema and the changes of their vision after the treatment were examined during twelve months＇follow-up.RESULTS：After the treatment with photocoagulation , visual acuity of 21 eyes（18.7%） had been improved , 84 eyes （75.0%） remained the same , and vision of 7 eyes （6.3%） decreased . Macular edema was completely absorbed in 40 eyes （35.7%） , partly in 60 eyes （53.6%） , and was not absorbed at all in 12 eyes （10.7%）. 532nm frequency-doubled laser photocoagulation was more effective for localized edema than for diffuse edema （ P〈 0.01）.CONCLUSION：The method of 532nm frequency-doubled laser photocoagulation has been proved to be safe and effective in treating macular edema caused by retinal angiopathy.