经皮椎体成型术对脊椎转移癌患者止痛效果的评价

EVALUATION OF THE ANALGESIC EFFECT OF PERCUTANEOUS VERTEBROPLASTY FOR PATIENTS WITH VERTEBRAL METASTASES

目的:评价经皮椎体成型术对脊柱转移癌患者减轻背痛症状的疗效。方法:从2005年1月至2009年4月51例患者共101个椎体进行了经皮椎体成型术,术前及随访终点使用PI-NRS疼痛评估系统(0分为无疼痛,10分为最严重的疼痛)对患者进行疼痛评分。同时记录患者镇痛药的使用情况。疼痛评分减低至少2分认为临床有效。结果:全部患者术后均无严重并发症发生。随访1-9个月(平均3.6个月),51例患者中48例(94%)治疗后疼痛明显减轻,38例患者(75%)停用镇痛药治疗。结论:经皮椎体成型术对脊柱转移癌患者减轻背痛症状安全有效。

Objective ： To assess the effects of percutaneous vertebroplasty （PVP） for relieving back pain in patients with vertebral metastases. Methods： From January 2005 to April 2009, 51 patients underwent PVP on 101 vertebrae. Pain was evaluated with the pain intensity numeric rating scale （PI-NRS） （0 =no pain; 10 = the worst pain） before the procedure and at the end of follow-up. Analgesic drugs were recorded meanwhile. A reduction of at least two points of the PI-NRS score was considered clinically sig- nificant. Results： No severe complications were observed after operations. During follow-up for 1-9 months （mean 3.6 months）, a clinically significant pain reduction was observed in 48 of 51 patients （94%）, and 38 of 51 patients （75%） did not need analgesic drugs. Conclusion： Vertebral metastasesinduced back pain can be safely and effectively controlled by PVP.