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蒙药毛勒日达布苏-4对大鼠酒精性肝损伤的保护作用 被引量:3

Traditional Mongolian Medicine Maoleridabusu-4 in rat alcoholic liver injury in rats
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摘要 目的:蒙药毛勒日达布苏-4对大鼠酒精性肝损伤的保护作用。方法:采用W istar雄性大鼠105只,随机分为7组。采用白酒灌胃的方法建立大鼠酒精性肝损伤模型,同时给予蒙药毛勒日达布苏-4保护。检测血清中ALT、AST,HE染色观察肝脏的病理变化。结果:蒙药毛勒日达布苏-4降低血清中ALT、AST,明显改善肝组织脂肪样变。结论:蒙药毛勒日达布苏-4对酒精性肝损伤有明显的保护作用。 Objective Traditional Mongolian Medicine Maoleridabusu -4 in rat alcoholic liver injury in rats. Methods : Wistar male rats 105 were randomly divided into 7 groups. Liquor gavage method of using alcohol - induced liver injury rat model, while giving the Mongolian medicine Maoleridabusu -4 protection. Serum ALT, AST, HE staining of liver pathological changes. Results: Mongolian Medicine Maoleridabusu -4 scattered four lower serum ALT, AST, marked improvement in liver fat - like change. Conclusion : Traditional Mongolian Medicine Maoleridabusu - 4 pairs of alcohol - induced liver injury has obvious proteetive effect.
作者 王立军 孙树
出处 《中国民族民间医药》 2009年第24期8-9,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 蒙药毛勒日达布苏-4 酒精性肝损伤 保护作用 Mongolian medicine Maoleridabusu -4 alcohol -induced liver injury protective effect of
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参考文献2

  • 1蔡中起,刘传民.酒精性肝病研究现状[J].临床肝胆病杂志,1995,11(2):63-66. 被引量:5
  • 2杨致富 韩得恩 张新宇 等.大鼠酒精肝模型的制备.哈尔滨医科大学学报,2002,10(6):474-475.

二级参考文献2

  • 1Joan Caballería MD,Enrique Baraona MD,Ramón Deulofeu MD,Rolando Hernández-Mu?oz MD,Juan Rodés MD,Dr. Charles S. Lieber MD. Effects of H2-receptor antagonists on gastric alcohol dehydrogenase activity[J] 1991,Digestive Diseases and Sciences(12):1673~1679
  • 2Dr. Toru Takahashi MD,Tomoteru Kamimura MD,Hitoshi Asakura MD,Fumihiro Ichida MD. Hepatic lesions in alcoholic HBV carriers[J] 1991,Digestive Diseases and Sciences(9):1234~1242

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