胰岛素非依赖型糖尿病人群筛检的数量化方法

A Quantitative Method for Mass Screening of NIDDM

在人群的胰岛素非依赖型糖尿病（ＮＩＤＤＭ）危险因素病例对照研究的基础上，应用模糊数学的原理和方法，通过对糖尿病有关影响因素的数量化，建立了用于人群筛检的数学模型，对８７３４名２０～７４岁自然人群为研究对象的实际应用结果表明，随着数量化方法的隶属度（ＡＤ）值的增加，人群中糖尿病的患病风险亦随之增高，当判别阈值定为０．３时，对人群中既往糖尿病和新诊断糖尿病判别的灵敏度分别为７１．２６％和６０．９８％，特异度为７２．０７％。本法简便，易行，经济，有利于获得满意的受检率，可用于个体和群体（社区）的患病危险度测定及健康教育。

Based on a case control study on the risk factors of NIDDM,the risk factors of the disease was quantified and a mathematical model for the mass screening of the disease was developed according to some principles and methods of fuzzy mathematics.A general population sample of 8734 subjects,age 20～74 years,were tested and actual effectiveness of the method was evaluated.The results showed that the prevalence risk of NIDDM in the population was elevated as the increase of attributable degree(AD)of the method.When the identifying threshold value was set up to 0 3,the sensitivities for identifying diagnosed and undiagnosed NIDDM were 71 26% and 60 98%,respectively,and the specificity was 72 07%.The significant benefits of this quantitative method were simple,economical and helpful to obtain a satisfactory response rate.The method could be used in health education and identifying people(community)at high risk for undiagnosed diabetes.It was prediced that this quantitative method would serve as an effective and useful tool for mass screening of NIDDM.