腰骶椎前路螺旋融合笼在椎弓峡部裂模型上的生物力学表现

Biomechanical Display of Lumbosacral Anterior Threaded Fusing Cage on Isthmic Spondylolysis

目的制成近似临床腰骶椎峡部裂的病理模型，定量测试前路螺旋融合笼（ａｎｔｅｒｉｏｎｆｕｓ－ｉｎｇｃａｇｅ，ＡＦＣ）对该模型的稳定效果。方法使用４具人尸腰骶椎骨制成空白运动节段标本，用线锯锯断椎弓峡部法制成峡部裂模型标本，再分别用单纯骨块、ＡＦＣ置入模型标本椎间隙以固定该节段，测试以上４种状态下节段标本的应变、位移、刚度。结果该模型标本较对照空白标本刚度显著下降，ＡＦＣ固定后刚度显著增加。结论（１）该峡部裂模型基本符合本试验的要求；（２）Ｌ５Ｓ１椎间隙正中放置１枚ＡＦＣ，Ｌ４，５椎间隙左前外斜向放置１枚ＡＦＣ均明显提高了峡部裂模型标本的稳定性，较同部位单纯植骨有更好的稳定效果。

Aim To study the biomechanical display of lumbosacral anterior threaded fusing cage on isthmic spondylolysis models. Methods Four lumbosacral spinal specimens of human were used to manufacture the intact segmental specimen, then the specimen models were worked out by cutting the isthmic of intact specimens with wire saw, and then one pure bone towel or one anterior fusing cage (AFC) was inserted separately into the model's interbody space to stable the model. Finally, all of the specimens' stiffness of the upper four conditions was measured. Results Comparing with the intact specimens, the specimen models decreased significantly and the AFC specimens increased significantly in stiffness. Conclusion One AFC, that was located into either the middle of L 5S 1 interbody space or left lateral obliquely of L 4,5 interbody space, has obtained more significant effect in terms of stability of the specimen models than one pure bonetowel.