脑磁图在伴发癫癎的颅内肿瘤手术中的应用

Application of MEG in operation of intracranial tumor concomitanted with seizures

目的探讨脑磁图在伴发癫癎的颅内肿瘤手术中的应用。方法应用CTF脑磁图系统对20例伴发癫癎的颅内肿瘤患者行术前致癎灶定位,术中结合神经导航系统和皮层脑电描记指导致癎灶的处理。结果 16例肿瘤全切除,4例次全切除,致癎灶均获处理,术后癫癎停止发作20例;随访24～36个月,术后1月及15月各1例再次出现癫癎发作,余18例无发作,9例停药。结论伴发癫癎的颅内肿瘤,脑磁图能够较好的定位致癎灶,在切除肿瘤的同时指导致癎灶的处理。

Objective To explore the clinical applications of magnetoencephalograhy（MEG） in operation of intracranial tumors with seizures. Method Positioned by MEG before the operation, the epileptic focus of 20 patients were treated associated with neuronavigation system and cortical electrode monitoring. Result Of 20 patients, total resection was achieved in 16 and subtotal resection in 4. And all epileptic focus was given treatment. The following up from 24 to 36 months showed that 18 patients were free from seizure, 9 were with drug withdrawal, only 2 occurred again which one occurred after one month since the operation and another occurred after 15 months. Conclusion MEG is important in positioning the epileptic focus and resetting tumors in the treatment of intraeranial tumor with seizure.