庚型肝炎病毒RT-PCR检测

RT PCR DETECTION OF HEPATITIS G VIRUS

目的：调查石家庄地区庚型肝炎病毒（ＨＧＶ）的感染状况。方法：用聚合酶链反应（ＰＣＲ）法对５８例病毒性肝炎进行了ＨＧＶＲＮＡ检测。结果：证实了石家庄地区有ＨＧＶ感染存在，在非甲型～戊型肝炎中，ＨＧＶＲＮＡ的阳性率为２０％。在乙型、丙型肝炎病毒所致的慢性肝炎、肝炎肝硬化中，分别有１６．６７％、１４．２９％的病例重叠有ＨＧＶ感染。结论：严格掌握输血指征，筛查献血员，杜绝医源性感染，将对控制ＨＧＶ感染大有益处。

Objective:To investigate hepatitis G virus(HGV) infection in Shijiazhuang district.Methods:HGV RNA was detected by polymerase chain reaction(PCR) in 58 patients with hepatitis.Results:There was HGV infection in Shijiazhuang district.The HGV RNA positive rate was 20% in non A～E hepatitis.The HGV superinfection rates in HBV/HCV chronic hepatitis and liver cirrhosis patients were 16.67% , 14.29% respectively.Conclusion:Mastering blood transfusion indication strictly,screening blood donor,and prohibiting iatrogenic infection are helpful for controlling HGV infection.