摘要
对雌性小鼠进行自体及胚胎异体卵巢移植，于移植前、后检查动情周期，并于移植后进行组织学观察和血清孕酮放射免疫测定，探讨移植卵巢的生长发育以及胚胎卵巢移植的最佳时机。结果显示：双侧自体移植１４ｄ以后，移植卵巢的结构与正常卵巢组织没有明显的区别；血清孕酮水平接近正常，动情周期恢复。胚胎１７～１９ｄ的卵巢移植７～１４ｄ，卵巢中也可见到原始卵泡和窦前卵泡。结果提示：妊娠１７ｄ以后的胚胎卵巢具有较低的免疫原性，移植后有可能发育成熟，但其生长比成体组织慢。
Ovary autotransplantation and fetal ovary allotransplantation were performed in female mice. Estrus cycle was observed before and after transplantation. Histological study and radioimmunoassay were used to study the graft growth, and the proper time for fetal transplantation. 14 d after ovary autotransplantation, the ovarian structure showed normal. Serum P level increased. The estrus cycle reoccured. 7 to 14 d after fetal ovary (17th day gestation) allotransplantation, primordial follicles and preantral follicles could be found. This study indicates that fetal ovary (17th day of gestation) can grow and become mature after allotransplantation.
出处
《首都医科大学学报》
CAS
1998年第3期209-212,共4页
Journal of Capital Medical University
关键词
卵巢移植
自体
胚胎
ovary
transplantation
fetal
estrus cycle
