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大鼠脑缺血再灌注的MR扩散加权成像与水通道蛋白-4表达的相关性研究 被引量:7

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摘要 脑血管疾病是严重危害人类健康的常见病、多发病,具有高发病率、高死亡率、高致残率等特点。脑血管病居全球死亡病因的第2位,其中脑梗死占脑血管病总数的70%左右。一旦临床上出现脑梗死,早期诊断和及时溶栓治疗是惟一能规避其高死亡率、高致残率等严重并发症的可靠保证。研究表明,早期脑梗死的病理改变主要是细胞内水肿,水通道蛋白4(aquaporin-4,AQP4)参与其形成。
出处 《中华放射学杂志》 CAS CSCD 北大核心 2009年第12期1319-1321,共3页 Chinese Journal of Radiology
基金 国家博士后科学基金资助项目(20080431308) 四川省卫生厅资助课题(070374)
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