复发性外阴阴道念珠菌病患者的病原菌分析

Study on the pathogen distribution of recurrent vulvovaginal candidosis

目的了解复发性外阴阴道念珠菌病患者的念珠菌菌种分布。方法采集外阴阴道念珠菌病患者的标本,用CHRO Magar Candida显色培养基及生物梅里埃API20CAUX酵母菌鉴定系统鉴定念珠菌的菌种。结果289例患者的阴道分泌物标本中,共检出念珠菌224株,检出率为77.51%。其中复发性外阴阴道念珠菌病患者的分泌物标本89例,检出72株。临床分离的念珠菌以白念珠菌居多共168株,占75.00%;其次为近平滑念珠菌19株(8.48%),克柔念珠菌11株(4.91%),其他为热带念珠菌、光滑念珠菌等。结论复发性外阴阴道念珠菌病患者以白念珠菌感染占明显优势,其他有近平滑念珠菌。

Objective To study distribution of candida strains in patients with candidal vaginitis. Methods Candida strains were identified and characterized by CHROMagar Candida medium and Bliom API 20C AUX. Results There were 224 candida strains detected in 289 specimens of candidal vaginal secretion（77.5 % ） , of which 72 candida strains were identified in 89 specimen of recurrent vulvovaginal candidosis. Most of these strains were candida albicans; 168（75%） and 19 （8%） strains were candida parapsilosis, and 11（5%） strains were candida tropicalis. Conclusions Candida strains isolated from patients with recurrent vulvovaginal candidosis are predominately candida albicans, and a few are eandida parapsilosis and candida tropicalis.