硒对肺炎支原体肺炎病程影响的研究

Study on Fugu Medicated Therapeutic Prescription

为观察硒对肺炎支原体肺炎的治疗效果，采用双盲随机对照实验：选择住院支原体肺炎患儿，分为补硒组２６例，病例对照组２１例，正常组２１例。一次补硒量为１ｍｇ亚硒酸钠，对照病例组给予常规治疗。临床结果表明，与对照组相比，治疗后补硒组的症状和体征缓解天数均有不同程度缩短（Ｐ＜０．０５），补硒组白细胞硒和谷胱甘肽过氧化物酶水平显著上升（Ｐ＜０．０５），细胞免疫功能有所改善。本研究结果提示，感染时机体内硒的代谢加速，使硒的需要量增加。

The Fugu medicated therapeutic prescription (FGMTP) composed of the medicinal herbs with food usage was investigated on the nutrition components and its antitunor activity. The results showed that the ratios of thermogenesis of three calorifacient nutrients were protein (12.34%), fat(5.62%) and carbohydrates (82.0%), respectively. The IC50 values of the water extract from this prescription against the 7901 or K562 cell line colony formations were 3.59g/L and 25.74 mg/L, and the maximal inhibitory rates against both cell line colony formations were 53.2% and 58.9%; respectively. The maximal inhibitory rates against HepA and S180 transplantation tumors were 35.3% and 35.0%, respectively. It is concluded that the FGMTP possessed obvious antitumor effects.