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氧化低密度脂蛋白抗体与冠心病严重程度及Gensini积分的相关性 被引量:3

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摘要 目的研究氧化低密度脂蛋白抗体(ox-LDLAb)与冠心病严重程度及Gensini积分的相关性。方法选择行冠状动脉造影的154例患者,分为正常对照组、不稳定心绞痛(UAP)组、急性心肌梗死(AMI)组,ELISA法测定三组血清ox-LDLAb水平,并根据造影结果行Gensini积分。结果UAP组和AMI组ox-LDLAb均低于对照组(P<0.05);ox-LDLAb与Gensini积分呈显著负相关(r=-0.334,P=0.000),ox-LDLAb与高密度脂蛋白呈显著正相关(r=0.263,P=0.004),ox-LDLAb为急性冠脉综合征的保护性因素。结论ox-LDLAb可能具有抗动脉粥样硬化的作用。
出处 《山东医药》 CAS 北大核心 2009年第41期37-38,共2页 Shandong Medical Journal
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