伴运动性失语脑卒中患者抑郁的临床研究

Clinical study of depression in stroke patients with broca aphasia

目的探讨伴运动性失语脑卒中患者的抑郁状况。方法采用失语抑郁量表(ADRS)及Zung抑郁自评量表(SDS)对首次卒中伴运动性失语(失语组,66例)患者进行测评,并与无失语卒中患者(对照组,66例)进行比较。结果失语组抑郁发生率(62.12%)明显高于对照组(25.76%)(P<0.01);失语组中、重度抑郁发生率(41.46%、12.20%)明显高于对照组(29.41%、0;P<0.05～0.01);且抑郁发生率随失语程度加重而显著增高(均P<0.01)。结论卒中伴运动性失语患者抑郁的发生率明显增高,且抑郁的发生率与失语严重程度相关。

Objective To investigate the depression in stroke patients with broca aphasia. Methods Aphasia Depression Rating Scale （ADRS） and Zung＇ s self-rating depression scale （SDS） were applied in patients on the first stroke with broca aphasia （ Aphasia group, 66 cases）. The results were compared with stroke patients without aphasia （control group, 66 cases）. Results Compared to control group, the incidence of depression in Aphasia group was significantly higher（62.12% vs 25.76% ,P 〈 0. 01 ） ; while, the rates of moderate or severe depression in Aphasia group were also significantly higher （41.46% vs 29.41% ; 12.20% vs 0;P 〈 0. 05 - 0.01 ）. The incidence was increasd with the severity of broca aphasia （ all P 〈 0. 01 ）. Conclusion The incidence of depression in stroke patients with broca aphasia is significantly high, and closely related to the severity of broca aphasia.