肠内免疫营养及其临床应用

Introduction to Effects and Clinical Applications of Enteral Immunonutrition

目的探讨主要免疫营养素的作用和机理,并介绍其在临床肠内营养应用中的进展。方法采用文献复习的方法,对肠内免疫营养作用及临床应用情况的相关文献加以综述。结果合理实施肠内免疫营养可以改善患者营养状态、增强免疫力,达到降低感染率和缩短住院时间的效果,消化道肿瘤、移植、慢性肝病、急性胰腺炎等患者可从中受益。但作为一种新型的营养支持方法,其在危重患者中的应用仍存在争议。结论肠内免疫营养在消化道肿瘤、器官移植等患者的营养支持方面发挥着重要作用,但仍须不断进行研究。

Objective To study the effects and mechanisms of major immune nutrients and to introduce the progresses of clinical applications about enteral immunonutrition.Methods The related literatures about the effects and clinical applications of enteral immunonutrition were reviewed.Results Infection rate can be reduced and the hospitalization can be shortened as a result of the improved nutritional status and immune competence of patients which can be enhanced by reasonable enteral immune nutrition.Most of the patients suffering from serious diseases can benefit from enteral immunonutrition, such as gastrointestinal cancers, post transplantation complications, chronic liver disorders, acute pancreatitis and so on. However, as a new nutrition therapy, the clinical use of enteral immunonutrition in critically ill patients is still controversial. Conclusions Enteral immunonutrition plays an important role in the nutritional support of patients with serious diseases, such as gastrointestinal cancers, organ failures. However, much work remains to be done.