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硫胺素(维生素B1)缺乏性Wernicke脑病一例 被引量:5

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摘要 改革开放三十多年来,人们的生活水平有了很大提高,以往的低热量营养缺乏性疾病已比较少见;但是随着生活方式的改变,一类由不良生活方式所致的营养缺乏性疾病在临床上开始多见。其中之一就是长期慢性酗酒者所患的硫胺素(维生素B1)缺乏性Wernicke脑病。在发达国家,90%以上的Wernicke脑病与酗酒有关,其他原因有长期肠外营养而忽视了维生素的补充。本病是一种急性,或者亚急性发生的以精神智能障碍、眼肌麻痹(复视)、
出处 《罕少疾病杂志》 2009年第6期53-55,共3页 Journal of Rare and Uncommon Diseases
关键词 维生素B1 脑病
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参考文献7

  • 1Thomson, A. B. (2000) Mechanisms of vitamin deficiency in chronic alcohol misusers and the development of the WernickeKorsakoff Syndrome. Alcohol and Alcoholism 35, Suppl. 1, 2 7.
  • 2Diseases of the nervous system due to neutritional deficiency in Adams and Victor's Principles of Neurology, eighth edition by Allan H. Ropper, Robert H. Brown, The McGraw-Hill Companies, Inc, 2005, PP 983-988.
  • 3宫旭海,李雪松,杨凤民,何小花,刘江华,夏圣梅.Wernicke脑病致小脑可逆性脱髓鞘性改变1例[J].中国CT和MRI杂志,2004,2(1):64-64. 被引量:3
  • 4Victor, M., Adams, R. D. and Collins, C. H. (1989) The Wernicke Korsakoff Syndrome and Related Disorders due to Alcoholism and Malnutrition. Davis, Philadelphia, PA.
  • 5Harper, C. (1979) Wernicke' s encephalopathy: a more common disease than realised. Journal of Neurology, Neurosurgery and Psychiatry 42, 226 231.
  • 6Thomson, A. D., Baker, H. and Leevy, C.H. (1970) Patterns of 35S-thiamine hydrochloride absorption in the malnourished alcoholic patient. Journal of Laboratory and Clinical Medicine 76, 34 45.
  • 7Reidling, J. C. and Said, H. M. (2005) Adaptive regulation of intestinal thiamine uptake: molecular mechanisms using wildtype and transgenic mice carrying hTHTR-1 and 2 promoters. American Journal of Physiology: gastrointestinal and Liver Physiology 228, 61127 1134 Epub 2005 Feb 10.

二级参考文献2

  • 1[1]刘增恒,杨广富,主编.临床脑病.沈阳:辽宁科学技术出版社,1992.269.
  • 2鲁晓燕,张挽时,李立伟,郭英,高晓兰,赵俊平.Wernicke脑病[J].空军总医院学报,1995,11(2):107-108. 被引量:11

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