显微外科手术治疗单纯第三脑室内颅咽管瘤

Microsurgical treatment of purely intrinsic third ventricnla craniopharyngioma

目的报道单纯第三脑室内颅咽管瘤临床特点和显微外科手术治疗的临床疗效。方法回顾性研究分析显微外科手术治疗的单纯第三脑室内颅咽管瘤8例，对肿瘤的临床表现、内分泌学和影像学特点、手术人路选择和术后并发症进行系统分析。结果肿瘤全切除7例，次全切除1例，术后发生暂时性中枢性尿崩症5例，一过性的电解质平衡失调6例，术后无死亡病例。结论单纯第三脑室内颅咽管瘤有其自身临床特点，选择适当的手术入路，显微外科手术切除肿瘤可取得较好疗效。

Objective To study the clinical characteristics, microsurgical methods and results of treatment of the purely intrinsic third ventricular craniopharyngioma. Methods Eight cases of craniopharyngiomas located purely in intrinsic third ventricula which were treated microsurgically were analyzed retrospectively. Their clinical manifestations, endocrinal examination, CT and MRI images, choice of operactive approaches and post-operative complications were studied. Results Total tumor removals were achieved in 7 cases, and subtatol tumor removal in 1 case. Temporary central diabetes insipidus occurred in 5 cases, and pefioperative water and elecctrolyte imbalance in 6 cases. No patient died in this series. Conclusion According to clinical characteristic of purely intrinsic third ventricular craniopharyngioma, microsurgical technique is a safe and effective method for treatment by a resonable surgical approaches.