顽固性心绞痛的治疗进展

Progress in the therapy of refractory angina pectoris

顽固性心绞痛是指存在客观的心肌缺血的依据,心绞痛症状严重,最大限度内科治疗无效,不适合介入或手术治疗,或多次治疗无效的心绞痛。由于人类寿命的延长,这部分患者越来越多,这对心绞痛的治疗提出了新的要求。目前对顽固性心绞痛的治疗包括非常规药物治疗、治疗性血管再生、经皮激光血运重建术、脊髓刺激、增强型体外反搏,心脏冲击波疗法及经皮心肌冷冻疗法等,新的治疗方法也在不断探索中。

Refractory angina pectoris is an angina, with an objective evidence of myocardial ischemia and persistence of symptoms despite optimal medical therapy, life style modification treatments, and revascularization therapies. With the increase in life expectancy, more and more patients with angina pectoris refractory requires a new antianginal therapeutics. Currently, there were the non-conventional therapies to treat the refractory angina pectoris, which include pharmacotherapy, therapeutic angiogenesis, percutaneous myocardial laser revascularisation, spinal cord stimulation, enhanced external counterpulsation. Recently, some novel strategies such as cardiac shock wave therapy and percutaneous myocardial cryotherapy are also trying to treat the refractory angina pectoris.