期刊文献+

奈达铂联合5-Fu治疗中晚期宫颈癌32例 被引量:5

下载PDF
导出
摘要 目的探讨奈达铂联合5-Fu治疗中晚期宫颈癌的疗效及毒副反应。方法经病理或细胞学确诊的68例中晚期宫颈癌随机分为两组,单纯放疗组36例,放化疗结合组32例,治疗后1月进行疗效及毒副作用评价。结果与单纯放疗组相比,放化疗结合组治疗有效率明显提高(P〈0.05);两组治疗方案均存在不同程度的白细胞和血小板下降、消化道反应、静脉炎和脱发;其中以白细胞下降和消化道反应为主,发生率均超过50%;两组之间比较,各毒副反应发生率无明显差异(P〉0.05)。结论奈达铂联合5-Fu放疗治疗中晚期宫颈癌可提高近期疗效,不影响放疗进程,毒副反应无明显增加,值得临床推广使用。
出处 《中国中医药现代远程教育》 2009年第12期223-224,共2页 Chinese Medicine Modern Distance Education of China
  • 相关文献

参考文献1

二级参考文献36

  • 1Sumi H,Ohtsu A,Boku N,et al.A case of inoperable esophageal carcinoma with hepatic and nodal metastases which showed a long-term survival after chemoradiotherapy including nedaplatin [J].JpnJ Clin Oncol,2000,30(9):406~409
  • 2Kaneko K,Ito H,Ito T,et al.A case of esophageal carcinoma with multiple liver metastases successfully treated with nedaplatin (NDP) and 5-fluorouracil (5-FU) combined with radiotherapy[J].Gan To Kagaku Ryoho,2001,28(6):831 ~834
  • 3Hirabayashi Y,Okada E.Combination chemotherapy with 254-S,ifosfamide and peplomycin for advanced or recurrent cervical cancer[J].Cancer,1992,71:2769 -2775
  • 4Adachi S,Ogasawara T,Yamasaki N,et al.A pilot study of nedaplatin and etoposide for recurrent gynecological malignancies [J].Oncol Rep,1998,5(4):881-884
  • 5Ito K,Adachi S,Itani Y,et al.A dose-finding study of nedaplatin and cyclophosphamide for patients with gynecological malignancies[J].JpnJ Clin Oncol,1999,29(6):299-302
  • 6Adachi S,Ogasawara T,Wakimoto E,et al.Phase Ⅰ/Ⅱ study of intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical carcinoma[J].Cancer,2001,91 (1):74~ 79
  • 7Kodama J,Hashimoto I,Seki N,et al.Concurrent chemoradiotherapy for advanced cervical cancer-a pilot study [J].Gan To Kagaku Ryoho,2001,28(3):351-355
  • 8Adachi S,Ogasawara T,Tsubamoto H,et al.Intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical cancer[J].IntJ Clin Pharmacol Res,2001,21(3-4):105~110
  • 9Adachi S,Yamasaki N,Ogasawara T,et al.Combination chemotherapy using intravenous nedaplatin (254-S) and intraarterial cisplatin (CDDP) with transcatheter arterial embolization (TAE) for a patient with uterine cervical cancer: a case report[J].JpnJ Clin On
  • 10Kamiura S,Kobayashi K,Ohira H,et al.Concurrent chemoradiation therapy with nedaplatin for high-risk cervical cancer-clinical investigation of adverse events [J].Gan To Kagaku Ryoho,2001,28(7):979-986

共引文献175

同被引文献25

引证文献5

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部