超声检测颈动脉粥样硬化斑块与冠心病的相关性研究

Correlation between carotid atherosclerotic plaques on carotid sonography and coronary artery disease

目的探讨超声检测颈动脉粥样硬化斑块与冠心病的相关性。方法选择本院心血管内科住院拟诊冠心病患者89例行颈动脉超声检查,所有病例根据其冠状动脉造影检查结果分为冠心病(CAD)组52例与对照(CON)组37例,其中冠心病组根据心肌梗死诊断标准进一步分为非心肌梗死(non-MI)组及曾有心肌梗死病史(MI)组。超声检查时记录颈动脉粥样硬化斑块的发生情况,并对发现的粥样硬化斑块根据其超声特征分为稳定型和不稳定型斑块。对各组病例的斑块发生率及不稳定型斑块发生率进行统计学分析。结果CAD组的斑块发生率明显高于CON组(P<0.05),MI组的不稳定型斑块发生率明显高于non-MI组(P<0.05)。结论颈动脉粥样硬化斑块的发生与冠心病有明显相关性。颈动脉粥样硬化不稳定型斑块的存在与心肌梗死有相关性。

Objective To investigate the relationship between carotid atherosclerotic plaques on sonography and coronary artery disease（CAD）.Methods Totally,89 patients with suspected coronary artery disease were divided into CAD group and control group according to the results of coronary angiography.The CAD group was further divided into non-MI and MI groups according to the history of myocardial infarction before.All patients underwent carotid sonography and the atherosclerotic plaques were classified into stable and unstable plaques.The incidence rate of plaque was calculated and compared statistically.Results The incidence rate of plaque in CAD group was significantly higher than that in CON group（P0.05）.The incidence of unstable plaque was statistical different between the non-MI group and MI group（P0.05）.Conclusion The presence of carotid atherosclerotic plaques is related with the coronary artery disease.The unstable plaque on carotid sonography correlates with myocardial infarction.