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重组瘦蛋白对大鼠内分泌代谢的影响

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摘要 利用重组瘦蛋白进行动物饲养试验研究。结果表明:重组瘦蛋白对大鼠内分泌代谢指标有一定影响。腹腔注射6μg/g体重,连续注射瘦蛋白7d后,大鼠血清胰岛素水平明显下降,与对照组相比,降低了15.44%(P<0.05),但对大鼠血清葡萄糖水平则没有显著影响;禁食可明显抑制大鼠生长激素的分泌,同时禁食大鼠的血清游离T4、T3水平与正常进食的对照组相比分别下降了17.39%和18.88%(P<0.05),与禁食大鼠相比,注射瘦蛋白大鼠的T4水平升高了17.11%(P<0.01),接近正常对照组水平,但给予瘦蛋白的大鼠的T3水平与对照组相比仅升高了8.25%(P<0.05),表明给予重组瘦蛋白可对禁食引起的血清生长激素和游离T4、T3水平的降低起到纠正作用。
作者 艾薇 高士争
机构地区 保山学院生化系 云南农业大学动物营养与饲料重点实验室
出处 《饲料工业》 北大核心 2009年第24期48-50,共3页 Feed Industry
关键词 瘦蛋白 内分泌代谢 大鼠
分类号 S815.1 [农业科学—畜牧学]
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参考文献11

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饲料工业
2009年 第24期

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