摘要
采用反相高效液相色谱法，以Ｃ１８色谱柱，甲醇∶水（０．１％四乙基溴化胺）＝８５∶１５的流动相，于２２６ｎｍ处进行检测，测定了４Ｂ酸生产过程中所用原料及产品的含量，样品测试的回收率不小于９８％，对生产过程中对甲苯胺的转化率的测定则选用２５４ｎｍ为检测波长，用面积归一化法定量．用此法进行定量仅需１０ｍｉｎ，可用于４Ｂ酸生产过程的在线监控分析，据此选择出合适的反应时间为４ｈ．
The content of the raw materials and the products of the process period of 4B acid was determined by high performance liquid chromatography(HPLC) with C18 chromatographic column,MeOH∶H 2O(0.1% tetraethyl bromide amine) mobile phase which ratio is 85∶15,detected at 226 nm. The percent recovery of the measurement and test is not less than 98%. The percent conversion of p aminotoluene in the process period was determined at 254 nm and quantity analysed with method of proportion to one.This method only need 10 min to quantify and can be used to online monitoring analysis the process period of 4B acid,and hereby the suitable reaction time is 4 h.
出处
《郑州轻工业学院学报》
1998年第3期23-26,共4页
Journal of Zhengzhou Institute of Light Industry（Natural Science）
关键词
高速液体色谱
氨基苯磺酸
苯胺
二氯苯
high speed liquid chromatography
amino benzenesulfonic acid
anilines
dichlorbenzene
