治疗复发性外阴阴道假丝酵母菌病的探导

The treatment of recurrent vulvovaginal candidiasis:A review

目的探讨复发性外阴阴道假丝酵母菌病(RVVC)的治疗方法。方法确诊为RVVC的患者82例,用氟康唑加制霉菌素治疗至真菌学转阴后,随机分成2组:治疗组用上述抗真菌巩固后采用阴道乳酸杆菌活菌制剂治疗;对照组连续进行6个月的抗真菌巩固治疗。结果2组近期治愈率差异无显著性;而3个月复发率治疗组明显低于对照组,差异有显著性。结论乳酸杆菌活菌制剂(定君生)能够预防RVVC的复发。

Objective To discuss recurrent vulvovaginal candidiasis（RVVC） and its treatment.Method 82 patients diagnosed as having RVVC were given fluconazole and mycostain until their fungological detection results were negative.They were then randomly divided into 2 groups： the treatment group was given live preparation of Lactobacillus,while the control group continued the above anti-fungal consolidation treatment for 6 months.Result There was no significant difference between the short-term cure rates of the two groups,while the recurrence rate at 3 months of treatment group was lower than that of the control group,and the difference was statistically significant.Conclusion Live preparation of Lactobacillus（Ding Jun Sheng） can prevent the reccurence of RVVC.