Avastin治疗视网膜中央静脉阻塞后顽固性黄斑水肿的疗效

Avastin therapy for refractory macular edema secondary to central retinal vein occlusion

目的:观察Avastin玻璃体腔注射对视网膜中央静脉阻塞后顽固性黄斑水肿的疗效。方法:视网膜中央静脉阻塞后顽固性黄斑水肿患者随机分为治疗组(12只眼)和对照组(15只眼),治疗组予玻璃体腔注射Avastin2.5 mg,术后随访1个月,通过视力、OCT检查,观察黄斑水肿的治疗效果。结果:治疗组的视力较术前有显著提高,OCT检查示治疗组黄斑水肿消退明显,与对照组比较差异有显著性。结论:Avastin玻璃体腔注射治疗视网膜中央静脉阻塞后顽固性黄斑水肿,短期观察,有一定疗效。

Objective To observe the efficacy of intravitreal injections of avastin for refractory macular edema secondary, to central retinal vein occlusion. Methods All patients were randomly assigned to the study group （12 eyes） or the control group （ 15 eyes）. The study group received intravitreal injections of avastin of 2.5 mg. All patients were followed one month after the procedure and the efficacy of avastin was observed by optical coherence tomography （OCT） and visual acuity. Results Visual acuity was markedly improved and macular edema notably regressed on OCT in the study group, revealing significant differences between the two groups. Conclusion In a short-term follow-up, intravitreal avastin therapy is effective in the treatment of refractory macular edema seeondary to central retinal vein occlusion.