摘要
目的:探讨四磨汤对不同机能状态小鼠胃肠运动功能的影响。方法:观察不同剂量四磨汤对正常小鼠、阿托品所致胃肠抑制及新斯的明所致亢进小鼠胃内残留率和小肠推进率的影响。结果:四磨汤对正常小鼠胃排空和肠推进有促进作用,可不同程度地拮抗阿托品导致的胃肠抑制和新斯的明所致的胃肠亢进,且以中剂量组疗效最佳。结论:四磨汤对胃肠运动障碍有双向调节作用。
Objective： To investigate the effect of simo decoction on gastrointestinal motility in differ-functional status mice. Methods： To observe effects of different dosage simo-decoction on assay of gastric emptying and small intestinal propulsion in normal mice, gastrointestinal inhibition by atropine mice and hyper function by neostigmine mice. Results： Simo decoction can promote the gastric emptying and intestinal motility in normal mice, varying degrees resist gastrointestinal inhibition by atropine and hyper function by neostigmine. The best curative effect is middle dose group. Conclusion： Simo decoction can adjust gastrointestinal dysfunction with dual-direction regulation.
出处
《中医药导报》
2009年第12期64-66,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家重点基础研究计划(973)课题(2009CB523002)
湖南省中医药科研基金项目(209004)
关键词
四磨汤
胃肠功能
胃排空
肠推进
Simo decoction
Gastrointestinal function
Gastric emptying
Small intestinal propulsion
