大鼠中脑、内脏和躯体传入在旁巨细胞外侧核神经元的聚合(英文)

CONVERGENCE OF MIDBRAIN, VISCERAL AND SOMATIC INPUTS ONTO NEURONS IN THE NUCLEUS PARAGIGANTOCELLULARIS LATERALIS IN RATS

用细胞外记录的方法观察大鼠巨细胞旁外侧核（nucluesparagigantocellularislateris，PGL）对刺激中脑导水管周围背侧部（dorsalperiapueductoralgraymatter，dPAG）及腹外侧部（ventrolateralperiaqueductoralgraymatter，vPAG）、腓深神经（deepperonealnerve，DPN）、正中神经（mediannerve，MN）和内脏大神经（greatsplanchnicnerve，GSPL）的反应。这些神经元不仅对某一处刺激部位起反应，而且倾向于对其它任一刺激部位也起反应。89％（73／82）的神经元接受两处或两处以上来源的汇聚投射。60％（21／35）的神经元由于具有压力敏感性，并且其下行投射到脊髓的轴突具有慢的传导速度，因而被认为是心血管神经元。这些结果为PGL神经元在某些情况下的心血管整合功能提供新的证据。

Extracellular recordings were made in nucleus paragigantocellularis lateralis (PGL) of therat in response to stimulation of the dorsal periaqueductoral gray matter (dPAG ), ventrolateralperiaqueductuctoral gray matter(vPAG ), deep peroneal nerve (DPN ), median nerve (MN) and greatsplanchnic nerve (GSPL). Stimulation of dPAG or MN evoked mainly excitatory responses while the responsesto stimulation of vPAG were inhibitory. However, stimulation of GSPL or DPN Produced both inhibitory andexcitatory responses. These neurons were not only responsive to one stimulation site, but were likely responsiveto any other stimulation sites. Eighty-nine percent of cells tested (73/82) received convergent inputs from twoor more sites Sixty percent (21/35) of the neurons were identified as cardiovascular unts based on theirbarosensitivity and slow conduction velocities of the descending axons projecting into the spinal cord. Thisresult provided new evidence for the integrative function of neurons in PGL under some circumstances.