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左旋布比卡因胸段硬膜外阻滞用于乳腺癌改良根治术的麻醉效果观察 被引量:1

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摘要 目的观察左旋布比卡因胸段硬膜外阻滞用于乳腺癌改良根治术的麻醉效果及不良反应。方法40例行乳腺癌改良根治术的患者,随机分成两组:对照组使用0.375%布比卡因+0.5%利多卡因连续硬膜外阻滞,试验组使用0.375%左旋布比卡因+0.5%利多卡因连续硬膜外阻滞,每组20例。观察指标包括收缩压、舒张压、平均动脉压、心率、动脉血氧饱和度、SpO2,感觉阻滞起效时间、最高阻滞平面时间、麻醉维持时间、阻滞范围、麻醉质量、呼吸抑制程度及不良反应等。结果两组麻醉起效时间、麻醉维持时间、阻滞范围、麻醉质量差异无统计学意义(P>0.05),达最高阻滞平面时间试验组快于对照组(P<0.05)。两组呼吸抑制及不良反应发生率差异无统计学意义(P>0.05)。结论0.375%左旋布比卡因+0.5%利多卡因与0.375%布比卡因+0.5%利多卡因都能安全用于胸段硬膜外阻滞,满足乳腺癌改良根治术的麻醉要求,但左旋布比卡因较短的诱导时间和较低的神经及心脏毒性用于胸段硬膜外阻滞具有优越性。
出处 《苏州大学学报(医学版)》 CAS 北大核心 2009年第5期985-986,共2页 Suzhou University Journal of Medical Science
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参考文献5

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共引文献26

同被引文献15

  • 1朱波,龚志毅,叶铁虎,吴新民,孟美金,王庚,贾乃光,张亚军,刘春霞.国产0.5%盐酸左旋布比卡因用于硬膜外麻醉的可行性[J].中华麻醉学杂志,2004,24(8):582-584. 被引量:27
  • 2雷晓鸣,薛荣亮,钞海莲,张珍妮.不同长效局麻药用于上胸段硬膜外阻滞对患者术中循环及肺功能的影响[J].临床麻醉学杂志,2007,23(6):483-484. 被引量:4
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