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PI3K/Akt信号通路与小儿恶性实体肿瘤研究进展 被引量:3

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摘要 小儿恶性实体肿瘤包括神经母细胞瘤、肾母细胞瘤、肝母细胞瘤、横纹肌肉瘤等,是严重危害儿童健康的重要疾病之一。目前研究表明,细胞的存活、凋亡、分化或信号传导异常可能导致恶性肿瘤发生发展,其中以细胞信号传导异常尤为重要。已发现多条信号通路(如PI3K/Akt、MAPK通路,Ras途径等)与肿瘤关系密切,
出处 《临床小儿外科杂志》 CAS 2009年第6期57-59,68,共4页 Journal of Clinical Pediatric Surgery
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