血清降钙素原在儿童细菌感染性疾病诊断中的意义

Clinical significance of procalcitonin measurement of bacterial infectious diseases in children

目的探讨血清降钙素原(PCT)测定在儿童细菌感染性疾病中的诊断意义。方法收集各种儿童感染性疾病患儿129例,将其分为细菌感染和非细菌感染组。采用半定量的胶体金免疫结合法检测PCT,免疫比浊法测定C-反应蛋白(CRP)。结果细菌感染组PCT、CRP阳性率分别为90.0%、80.0%,非细菌感染组阳性率分别为21.3%、65.2%,两组比较PCT差异有统计学意义(P<0.01);CRP差异无统计学意义(P>0.05)。结论在儿童细菌感染性疾病诊断中,PCT检测可作为早期快速鉴别细菌感染的实验室新指标。

Objective To explore the diagnostic significance of proealationin（PCT） in children＇s bacterial infectious diseases. Methods 129 cases of children＇s infectious diseases were collected and divided into bacterial infection group and non--bacterial infection group. PCT and CRP were detected by semi-quantitative colloidal gold immunobindingmetry and immunoturbidimetry,respeetively. Results The positive rate of serum of PCT and CRP in bacterial infection group was 90.0% and 80.0% respectively,while in non--bacterial infection group it was 21.3% and 65.2 % ,respectively. Levels of PCT in bacterial infection group were significantly higher than that in non-bacterial infeetion（P〈0.01） ,differences were not found in CRP between the two groups（P〉0.05）. Conclusion PCT could be used as a new diagnostic marker for rapid identification of bacterial infectious in early stage of children＇s infectious diseases.