腺苷及其受体在急性肺损伤中的研究进展

Research advancement on adenosine and adenosine receptors in acute lung injury

急性肺损伤是临床常见的危重症，其发病机制复杂，病死率高。近年来的研究表明腺苷及其受体在急性肺损伤病理生理过程中发挥着重要的作用，主要包括信号转导、调控炎症反应、调节肺水肿清除等，这可能为今后治疗急性肺损伤提供新的途径。

Acute lung injury is a commonly critical case in clinic with complicated pathogenesis and high mortality. Recent studies have shown that adenosine and adenosine receptors play an important role in the pathophysiologic processes of acute lung injury, involving signal transduction, modulation of inflammatory response and regulation of alveolar fluid clearance, which may provide a new method in the treatment of acute lung injury in future.