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米达普利和缬沙坦联合使用对高血压患者血压昼夜节律的影响及护理对策 被引量:1

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摘要 目的探讨使用米达普利和缬沙坦对高血压患者血压昼夜节律的影响及护理对策。方法98例原发性高血压患者随机分为A组和B组各49例,A组给予清晨顿服米达普利10mg和缬沙坦80mg,B组给予清晨服用米达普利10mg,晚间服用缬沙坦80mg。分别对2组患者进行心理护理及高血压患者的常规护理。服药前及服药后每隔4周分别测定2组诊室血压和24h动态血压。结果2组患者用药后各时点收缩压和舒张压均低于用药前,差异均有统计学意义(P<0.05)。B组夜间平均收缩压、舒张压,晨峰血压升高程度,清晨收缩压,舒张压,脉压均较A组低,差异均有统计学意义(P<0.05)。结论米达普利和缬沙坦分次联合使用更能降低夜间血压、遏制清晨血压过度升高。护士应加强健康教育,指导患者合理、规范用药,可有效控制血压,减少并发症的发生。
出处 《临床合理用药杂志》 2009年第24期58-59,共2页 Chinese Journal of Clinical Rational Drug Use
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