HIV与CD4、CD8的相关性分析

Correlation analysis of HIV,CD4 and CD8

目的研究HIV/AIDS患者外周血的CD4、CD8及病毒载量的相关性,并探讨其临床意义。方法用流式细胞仪检测164例HIV/AIDS患者外周血的CD4、CD8及病毒载量,分析它们之间的相互关系。结果 CD4与病毒载量(LV)的结果比较显示随着CD4计数的上升病毒载量下降,但是CD4数值在200～400之间的区间内LV与CD4呈正比;CD4与CD8的结果比较显示从总体上观察CD4、CD8表现为正相关性,但是在CD4的200～400的区间CD8没有表现出明显的上升趋势;CD8与LV的结果显示在CD8数值的400～800的某一区间段CD8与LV呈正比,总体表现与病毒载量的关系十分复杂。结论在艾滋病的发病过程中与CD4、CD8及病毒载量密切相关,CD4数值在200～400区间内,CD8与LV均表现为与其他区间不同变化规律。

Objective To study the relevance of HIV/AIDS patients＇ circumference blood＇s CD4, CD8 and the viral load capacity, and discuss the clinical significance. Methods Examine 164 examples of HIV/AIDS patients＇ circumference blood＇s CD4, CDS, the viral load capacity and analyzes between them the reciprocity. Results The analysis results of CD4 and LV shows： with the rise of CD4＇s number, the viral load capacity is dropping, but if the number of CIM is between 200 - 400, LV and CD4 is being proportional; CD4 and the CD8 result showed; As a whole observes CD4 and CD8 performance for the relevance, but it had not displayed the obvious trend of escalation in CD4 200 - 400 sector CD8 ; the analysis result of CD8 and LV shows that during some area compartment of CD8 400 - 800, CD8 and LV present ratio. Conclusion In AIDS＇s morbidity process, disease＇s occurrence development has close relationship with CD4, CD8 and viral load capacity. In the CD4 digit＇s 200 -400 sectors, CD8 and LV display for and other sector different change rule.